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Articles from Syros Pharmaceuticals

Syros Announces Topline Data from SELECT-MDS-1 Phase 3 Trial of Tamibarotene in Higher-Risk Myelodysplastic Syndrome with RARA Gene Overexpression
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that the SELECT-MDS-1 Phase 3 trial evaluating tamibarotene in combination with azacitidine in newly diagnosed higher-risk myelodysplastic syndrome (HR-MDS) patients with RARA gene overexpression did not meet its primary endpoint of complete response (CR) rate. Tamibarotene is Syros’ proprietary oral, selective, retinoic acid receptor alpha (RARα) agonist.
By Syros Pharmaceuticals · Via Business Wire · November 12, 2024
Syros Reports Third Quarter 2024 Financial Results and Provides a Business Update
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today reported financial results for the quarter ended September 30, 2024 and provided a business update.
By Syros Pharmaceuticals · Via Business Wire · October 31, 2024
Syros to Report Third Quarter 2024 Financial Results on Thursday, October 31, 2024
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that it will host a live conference call and webcast at 8:30 a.m. ET on Thursday, October 31, 2024 to report its third quarter 2024 financial results and provide a business update.
By Syros Pharmaceuticals · Via Business Wire · October 24, 2024
Syros Pharmaceuticals to Present at Upcoming Medical and Investor Conferences
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that it will present additional data from the randomized portion of the SELECT-AML-1 Phase 2 clinical trial at the Society of Hematologic Oncology (SOHO) Annual Meeting taking place September 4-7, in Houston, Texas. Additionally, Syros announced that company management will participate in the H.C. Wainwright 26th Annual Global Investment Conference, being held September 9-11 in New York City.
By Syros Pharmaceuticals · Via Business Wire · August 27, 2024
Syros Provides Update on SELECT-AML-1 Phase 2 Clinical Trial
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that it will discontinue enrollment in the SELECT-AML-1 Phase 2 clinical trial evaluating the triplet regimen of tamibarotene in combination with venetoclax and azacitidine compared to the doublet regimen of venetoclax and azacitidine in newly diagnosed, unfit patients with acute myeloid leukemia (AML) and RARA gene overexpression. This decision is based on the results of a prespecified interim analysis of the trial.
By Syros Pharmaceuticals · Via Business Wire · August 12, 2024
Syros Reports Second Quarter 2024 Financial Results and Provides a Business Update
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today reported financial results for the quarter ended June 30, 2024 and provided a corporate update.
By Syros Pharmaceuticals · Via Business Wire · July 31, 2024
Syros to Report Second Quarter 2024 Financial Results on Wednesday, July 31, 2024
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that it will host a live conference call and webcast at 8:30 a.m. ET on Wednesday, July 31, 2024 to report its second quarter 2024 financial results and provide a business update.
By Syros Pharmaceuticals · Via Business Wire · July 24, 2024
Syros to Host Webcast Event on Higher-Risk Myelodysplastic Syndrome and the Opportunity for Tamibarotene to Become the New Frontline Standard-of-Care for Patients with RARA Gene Overexpression
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that it will host a webcast event with medical experts to discuss the unmet need in higher-risk myelodysplastic syndrome (HR-MDS) and the opportunity for tamibarotene to transform the care of newly diagnosed patients with RARA gene overexpression. The event will take place on Tuesday, June 25, 2024, from 11:00 a.m. – 12:30 p.m. ET.
By Syros Pharmaceuticals · Via Business Wire · June 13, 2024
Syros Reports First Quarter 2024 Financial Results and Provides a Corporate Update
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today reported financial results for the quarter ended March 31, 2024 and provided a corporate update.
By Syros Pharmaceuticals · Via Business Wire · May 14, 2024
Syros to Participate in Upcoming Investor Conferences
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that company management will participate in a fireside chat at two upcoming investor conferences. Details are as follows:
By Syros Pharmaceuticals · Via Business Wire · May 7, 2024
Syros to Report First Quarter 2024 Financial Results on Tuesday, May 14, 2024
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that it will host a live conference call and webcast at 8:30 a.m. ET on Tuesday, May 14, 2024 to report its first quarter 2024 financial results and provide a corporate update.
By Syros Pharmaceuticals · Via Business Wire · May 7, 2024
Syros Receives Fast Track Designation from the FDA for Tamibarotene for the Treatment of Newly Diagnosed Unfit AML with RARA gene overexpression
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that the United States Food and Drug Administration (FDA) has granted Fast Track Designation to tamibarotene in combination with azacitidine and venetoclax for the treatment of newly diagnosed acute myeloid leukemia (AML) with RARA overexpression as detected by an FDA approved test in adults who are over age 75 years or who have comorbidities that preclude the use of intensive induction chemotherapy. Tamibarotene, an oral first-in-class selective retinoic acid receptor alpha (RARα) agonist, is currently being evaluated in combination with venetoclax and azacitidine for the treatment of newly diagnosed AML patients with RARA gene overexpression.
By Syros Pharmaceuticals · Via Business Wire · April 9, 2024
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced the grant of a restricted stock unit (RSU) award for 8,400 shares of Syros common stock to one newly hired employee in connection with commencing employment with Syros. This RSU was granted as a material inducement to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · April 2, 2024
Syros Reports Fourth Quarter and Full Year 2023 Financial Results and Provides a Corporate Update
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today reported financial results for the quarter and full year ended December 31, 2023 and provided a corporate update.
By Syros Pharmaceuticals · Via Business Wire · March 27, 2024
Syros Announces Completion of Enrollment of 190 Patients Necessary to Support Primary Endpoint Analysis in SELECT-MDS-1 Phase 3 Trial
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that the enrollment of 190 patients has been completed in the SELECT-MDS-1 Phase 3 clinical trial evaluating tamibarotene in newly diagnosed higher-risk myelodysplastic syndrome (HR-MDS) patients with RARA gene overexpression. This initial cohort of 190 patients is necessary to support the complete response (CR) primary endpoint analysis. Syros expects to report these pivotal data by the middle of the fourth quarter of 2024.
By Syros Pharmaceuticals · Via Business Wire · March 25, 2024
Syros to Report Fourth Quarter and Full Year 2023 Financial Results on Wednesday, March 27, 2024
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that it will host a live conference call and webcast at 8:30 a.m. ET on Wednesday, March 27, 2024 to report its fourth quarter and full year 2023 financial results and provide a corporate update.
By Syros Pharmaceuticals · Via Business Wire · March 20, 2024
Syros to Participate in TD Cowen 44th Annual Health Care Conference
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that its Chief Executive Officer, Conley Chee, will participate in a panel discussion at the TD Cowen 44th Annual Health Care Conference. Management will also be available for one-on-one meetings. Details are as follows:
By Syros Pharmaceuticals · Via Business Wire · February 27, 2024
Syros Highlights Anticipated 2024 Milestones to Deliver on the Value of Tamibarotene
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today highlighted anticipated 2024 milestones to deliver on the value of tamibarotene.
By Syros Pharmaceuticals · Via Business Wire · January 8, 2024
Syros Announces Pricing of $45.0 million Underwritten Offering of Common Stock and Pre-Funded Warrants
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, announced today that it has priced an underwritten offering of 4,939,591 shares of common stock at an offering price of $4.42 per share, and, in lieu of common stock to investors who so choose, pre-funded warrants to purchase 5,242,588 shares of its common stock at an offering price of $4.419 per pre-funded warrant, which would result in total gross proceeds of approximately $45.0 million, before underwriting discounts and commissions and offering expenses payable by Syros. All shares and pre-funded warrants are being offered by Syros. Closing of the offering is expected to occur on or about December 21, 2023, subject to customary closing conditions.
By Syros Pharmaceuticals · Via Business Wire · December 19, 2023
Syros Announces Encouraging Initial Data from Randomized SELECT-AML-1 Phase 2 Clinical Trial Evaluating Tamibarotene in Combination with Venetoclax and Azacitidine
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced strong and encouraging initial data from its ongoing SELECT-AML-1 Phase 2 trial evaluating tamibarotene, an oral, selective, retinoic acid receptor alpha (RARα) agonist, in combination with venetoclax and azacitidine in newly diagnosed, unfit patients with acute myeloid leukemia (AML) and RARA gene overexpression.
By Syros Pharmaceuticals · Via Business Wire · December 6, 2023
Syros to Participate in Upcoming Investor Conferences
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that company management will participate in a fireside chat at two upcoming investor conferences. Management will also be available for one-on-one meetings. Details are as follows:
By Syros Pharmaceuticals · Via Business Wire · November 21, 2023
Syros Reports Third Quarter 2023 Financial Results and Provides a Corporate Update
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today reported financial results for the quarter ended September 30, 2023 and provided a corporate update.
By Syros Pharmaceuticals · Via Business Wire · November 14, 2023
Syros to Report Third Quarter 2023 Financial Results on Tuesday, November 14, 2023
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that it will host a live conference call and webcast at 8:30 a.m. ET on Tuesday, November 14, 2023 to report its third quarter 2023 financial results and provide a corporate update.
By Syros Pharmaceuticals · Via Business Wire · November 7, 2023
Syros Announces Planned CEO Leadership Transition and Strategic Reorganization to Support Long-Term Business Growth and Maturation into a Commercial Biopharmaceutical Company
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced a strategic realignment to prioritize key development and pre-launch activities to advance tamibarotene for the frontline treatment of higher-risk myelodysplastic syndrome (HR-MDS) and acute myeloid leukemia (AML). Also today, Syros announced the retirement as Chief Executive Officer (CEO) of Nancy Simonian, M.D., and the appointment of Conley Chee, Syros’ Chief Commercial Officer (CCO) and Chief Business Officer (CBO), as CEO, effective December 2, 2023. Dr. Simonian will remain a member of the Syros Board of Directors following the transition.
By Syros Pharmaceuticals · Via Business Wire · October 2, 2023
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced the grant of restricted stock unit (RSU) awards for an aggregate of 20,650 shares of Syros common stock to two newly hired employees in connection with commencing employment with Syros. These RSUs were granted as a material inducement to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · September 7, 2023
Syros Reports Second Quarter 2023 Financial Results and Provides a Corporate Update
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today reported financial results for the quarter ended June 30, 2023 and provided a corporate update.
By Syros Pharmaceuticals · Via Business Wire · August 8, 2023
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced the grant of restricted stock unit (RSU) awards for an aggregate of 16,050 shares of Syros common stock to two newly hired employees in connection with commencing employment with Syros. These RSUs were granted as a material inducement to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · August 4, 2023
Syros to Report Second Quarter 2023 Financial Results on Tuesday, August 8, 2023
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that it will host a live conference call and webcast at 8:30 a.m. ET on Tuesday, August 8, 2023 to report its second quarter 2023 financial results and provide a corporate update.
By Syros Pharmaceuticals · Via Business Wire · August 1, 2023
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced the grant of a restricted stock unit (RSU) award for 9,000 shares of Syros common stock to one newly hired employee in connection with commencing employment with Syros. This RSU was granted as a material inducement to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · July 5, 2023
Syros to Present at Sidoti June 2023 Virtual Small-Cap Conference
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that its Chief Executive Officer, Nancy Simonian, M.D., will present a corporate overview at the Sidoti June 2023 Virtual Small-Cap Conference. Management will also be available for one-on-one meetings. Details are as follows:
By Syros Pharmaceuticals · Via Business Wire · June 8, 2023
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced the grant of restricted stock unit (RSU) awards for an aggregate of 29,250 shares of Syros common stock to three newly hired employees in connection with commencing employment with Syros. These RSUs were granted as a material inducement to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · June 1, 2023
Syros Presents Data from Phase 1/1b Clinical Trial of SY-5609 in Advanced Solid Tumors at ASCO Annual Meeting
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced new clinical data from the Phase 1/1b clinical trial evaluating SY-5609, its highly selective and potent inhibitor of CDK7, in patients with relapsed/refractory pancreatic ductal adenocarcinoma (PDAC), HR+ breast cancer and other solid tumors. The data will be presented in two posters at the 2023 American Society for Clinical Oncology (ASCO) Annual Meeting, taking place June 2-6, in Chicago, Illinois.
By Syros Pharmaceuticals · Via Business Wire · May 25, 2023
Syros Reports First Quarter 2023 Financial Results and Provides a Corporate Update
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today reported financial results for the quarter ended March 31, 2023 and provided a corporate update.
By Syros Pharmaceuticals · Via Business Wire · May 10, 2023
Syros to Present at JMP Securities 2023 Life Sciences Conference
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that its Chief Executive Officer, Nancy Simonian, M.D., will participate in a fireside chat at the JMP Securities 2023 Life Sciences Conference. Management will also be available for one-on-one meetings. Details are as follows:
By Syros Pharmaceuticals · Via Business Wire · May 9, 2023
Syros to Report First Quarter 2023 Financial Results on Wednesday, May 10, 2023
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that it will host a live conference call and webcast at 8:30 a.m. ET on Wednesday, May 10, 2023 to report its first quarter 2023 financial results and provide a corporate update.
By Syros Pharmaceuticals · Via Business Wire · May 3, 2023
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced the grant of restricted stock unit (RSU) awards for an aggregate of 17,800 shares of Syros common stock to two newly hired employees in connection with commencing employment with Syros. These RSUs were granted as a material inducement to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · May 2, 2023
Syros Reports Fourth Quarter and Full Year 2022 Financial Results and Provides a Corporate Update
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today reported financial results for the quarter and full-year ended December 31, 2022 and provided a corporate update.
By Syros Pharmaceuticals · Via Business Wire · March 2, 2023
Syros to Participate in Upcoming Investor Conferences in March
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that its Chief Executive Officer, Nancy Simonian, M.D., will participate in a panel discussion and present a corporate overview at two upcoming investor conferences in March. Management will also be available for one-on-one meetings. Details are as follows:
By Syros Pharmaceuticals · Via Business Wire · February 28, 2023
Syros to Report Fourth Quarter and Full Year 2022 Financial Results on Thursday, March 2, 2023
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that it will host a live conference call and webcast at 8:30 a.m. ET on Thursday, March 2, 2023 to report its fourth quarter and full year 2022 financial results and provide a corporate update.
By Syros Pharmaceuticals · Via Business Wire · February 23, 2023
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (NASDAQSYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced the grant of restricted stock unit (RSU) awards for an aggregate of 12,400 shares of Syros common stock to two newly hired employees in connection with their commencement of employment with Syros. These RSUs were granted as material inducements to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · February 9, 2023
Syros Announces Clinical Updates and 2023 Strategic Priorities
Syros Pharmaceuticals (NASDAQSYRS), a leader in advancing new standards of care for the frontline treatment of hematologic malignancies, today provided an update on its clinical development programs and outlined its strategic priorities for 2023.
By Syros Pharmaceuticals · Via Business Wire · January 9, 2023
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced the grant of restricted stock unit (RSU) awards for an aggregate of 14,200 shares of Syros common stock to four newly hired employees in connection with their commencement of employment with Syros. These RSUs were granted as material inducements to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · December 23, 2022
Syros Pharmaceuticals Announces Publication in Blood Advances Demonstrating the Potential of Tamibarotene in Patients with RARA Gene Overexpression, Supporting Ongoing Clinical Development in AML and MDS
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced a peer-reviewed publication of results from its completed biomarker-directed Phase 2 trial of tamibarotene in combination with azacitidine in newly diagnosed patients with acute myeloid leukemia (AML) who are not eligible for standard intensive chemotherapy. These findings support Syros’ ongoing evaluation of tamibarotene for the treatment of AML and myelodysplastic syndrome (MDS) patients with RARA overexpression. The paper, titled “Targeting RARA Overexpression with Tamibarotene, a Potent and Selective RARα Agonist, is a Novel Approach in AML,” was published online in Blood Advances on December 7, 2022 at https://doi.org/10.1182/bloodadvances.2022008806.
By Syros Pharmaceuticals · Via Business Wire · December 12, 2022
Syros Presents Safety Lead-in Data from SELECT-AML-1 Trial Evaluating Tamibarotene in Combination with Venetoclax and Azacitidine and Announces Plans to Initiate Randomized Portion of Phase 2 Trial
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced data from the safety lead-in portion of its ongoing SELECT-AML-1 Phase 2 trial evaluating tamibarotene, an oral, selective retinoic acid receptor alpha (RARα) agonist, in combination with venetoclax and azacitidine in newly diagnosed, unfit patients with acute myeloid leukemia (AML) and RARA gene overexpression. The data is being presented today in a poster session at the 64th American Society of Hematology (ASH) Annual Meeting, taking place in New Orleans, LA.
By Syros Pharmaceuticals · Via Business Wire · December 10, 2022
Syros to Host Virtual Event to Discuss Initial SELECT-AML-1 Data and Unmet Need in Newly Diagnosed Unfit Acute Myeloid Leukemia on December 10
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced that it will host a virtual event to discuss initial data from the safety lead-in portion of the ongoing Phase 2 SELECT-AML-1 clinical trial and to review the unmet need in newly diagnosed, unfit acute myeloid leukemia (AML). The event will be held on Saturday, December 10, 2022 beginning at 12:00 p.m. ET.
By Syros Pharmaceuticals · Via Business Wire · December 5, 2022
Syros to Participate at Piper Sandler 34th Annual Healthcare Conference
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced that its Chief Executive Officer, Nancy Simonian, M.D., will participate in a fireside chat at the Piper Sandler 34th Annual Healthcare Conference. Management will also be available for one-on-one meetings. Details are as follows:
By Syros Pharmaceuticals · Via Business Wire · November 22, 2022
Syros Pharmaceuticals Reports Third Quarter 2022 Financial Results and Provides a Corporate Update
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today reported financial results for the quarter ended September 30, 2022 and provided a corporate update.
By Syros Pharmaceuticals · Via Business Wire · November 14, 2022
Syros to Report Third Quarter 2022 Financial Results on Monday, November 14, 2022
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced that it will host a live conference call and webcast at 8:30 a.m. ET on Monday, November 14, 2022 to report its third quarter 2022 financial results and provide a corporate update.
By Syros Pharmaceuticals · Via Business Wire · November 7, 2022
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced the grant of restricted stock unit (RSU) awards for an aggregate of 22,610 shares of Syros common stock to three newly hired employees in connection with their commencement of employment with Syros. These RSUs were granted as material inducements to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · November 4, 2022
Syros Pharmaceuticals to Present Initial Data from SELECT-AML-1 Phase 2 Trial at 64th ASH Annual Meeting
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced that it will present initial data from the safety lead-in portion of its ongoing SELECT-AML-1 Phase 2 clinical trial at the 64th American Society of Hematology (ASH) Annual Meeting, taking place December 10-13, 2022 in New Orleans, LA. The SELECT-AML-1 trial is evaluating tamibarotene, Syros’ first-in-class selective retinoic acid receptor alpha (RARα) agonist, in combination with venetoclax and azacitidine in patients with newly diagnosed, unfit acute myeloid leukemia (AML) with RARA gene overexpression.
By Syros Pharmaceuticals · Via Business Wire · November 3, 2022
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (Nasdaq: SYRS), a leader in the development of medicines that control the expression of genes, today announced the grant of a restricted stock unit (RSU) award for 1,260 shares of Syros common stock to one newly hired employee in connection with the employee’s commencement of employment with Syros. These RSUs were granted as a material inducement to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · October 5, 2022
Syros to Present at H.C. Wainwright 24th Annual Global Investment Conference
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced that its Chief Executive Officer, Nancy Simonian, M.D., will present a corporate overview at the H.C. Wainwright 24th Annual Global Investment Conference. Management will also be available for one-on-one meetings. Details are as follows:
By Syros Pharmaceuticals · Via Business Wire · September 7, 2022
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (Nasdaq: SYRS), a leader in the development of medicines that control the expression of genes, today announced the grant of restricted stock unit (RSU) awards for an aggregate of 8,200 shares of Syros common stock to two newly hired employees in connection with their commencement of employment with Syros. These RSUs were granted as material inducements to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · September 2, 2022
Syros Reports Second Quarter 2022 Financial Results and Provides a Corporate Update
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today reported financial results for the quarter ended June 30, 2022 and provided a corporate update.
By Syros Pharmaceuticals · Via Business Wire · August 9, 2022
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (Nasdaq: SYRS), a leader in the development of medicines that control the expression of genes, today announced the grant of a restricted stock unit (RSU) award for 31,000 shares of Syros common stock to one newly hired employee in connection with the employee’s commencement of employment with Syros. These RSUs were granted as a material inducement to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · August 4, 2022
Syros Receives Positive Opinion on Orphan Drug Designation from the European Medicines Agency for Tamibarotene for the Treatment of MDS
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced that the European Medicines Agency (EMA) issued a positive opinion on the Company’s application for orphan drug designation for tamibarotene for the treatment of myelodysplastic syndrome (MDS). Tamibarotene, an oral first-in-class selective retinoic acid receptor alpha (RARα) agonist, is currently being evaluated in combination with azacitidine in the SELECT-MDS-1 Phase 3 trial for RARA-positive patients with newly diagnosed higher-risk MDS (HR-MDS).
By Syros Pharmaceuticals · Via Business Wire · August 3, 2022
Syros to Report Second Quarter 2022 Financial Results on Tuesday, August 9, 2022
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced that it will host a live conference call and webcast at 8:30 a.m. ET on Tuesday, August 9, 2022 to report its second quarter 2022 financial results and provide a corporate update.
By Syros Pharmaceuticals · Via Business Wire · August 2, 2022
Syros to Raise Approximately $190 Million Through Merger with TYME Technologies and Concurrent Private Placement
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, and TYME Technologies, Inc. NASDAQ:TYMENASDAQTYME)
By Syros Pharmaceuticals · Via Business Wire · July 5, 2022
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (Nasdaq: SYRS), a leader in the development of medicines that control the expression of genes, today announced the grant of restricted stock unit (RSU) awards for an aggregate of 48,400 shares of Syros common stock to two newly hired employees in connection with their commencement of employment with Syros. These RSUs were granted as material inducements to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · July 1, 2022
Syros to Present at JMP Securities Life Sciences Conference
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced that its Chief Executive Officer, Nancy Simonian, M.D., will participate in a fireside chat at the JMP Securities Life Sciences Conference. Management will also be available for one-on-one meetings. Details are as follows:
By Syros Pharmaceuticals · Via Business Wire · June 8, 2022
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (Nasdaq: SYRS), a leader in the development of medicines that control the expression of genes, today announced the grant of restricted stock unit (RSU) awards for an aggregate of 77,850 shares of Syros common stock to four newly hired employees in connection with their commencement of employment with Syros. These RSUs were granted as material inducements to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · June 3, 2022
Syros Pharmaceuticals Reports First Quarter 2022 Financial Results and Provides a Corporate Update
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today reported financial results for the quarter ended March 31, 2022 and provided a corporate update.
By Syros Pharmaceuticals · Via Business Wire · May 16, 2022
Syros to Report First Quarter 2022 Financial Results on Monday, May 16, 2022
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced that it will host a live conference call and webcast at 8:30 a.m. ET on Monday, May 16, 2022 to report its first quarter 2022 financial results and provide a corporate update.
By Syros Pharmaceuticals · Via Business Wire · May 9, 2022
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (Nasdaq: SYRS), a leader in the development of medicines that control the expression of genes, today announced the grant of restricted stock unit (RSU) awards for an aggregate of 136,750 shares of Syros common stock to six newly hired employees in connection with their commencement of employment with Syros. These RSUs were granted as material inducements to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · April 29, 2022
Syros Presents New Preclinical Data on its CDK12 Inhibitor Program at American Association for Cancer Research (AACR) Annual Meeting 2022
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced new preclinical data from our CDK12 inhibitor program, demonstrating robust anti-tumor activity of our oral, selective CDK12 inhibitors in models of breast, lung, and ovarian cancer, including in a PARP inhibitor resistant model. The data support the advancement of a development candidate from Syros’ CDK12 inhibitor program towards clinical development. These findings were presented in an e-poster as part of the American Association for Cancer Research (AACR) Annual Meeting 2022.
By Syros Pharmaceuticals · Via Business Wire · April 8, 2022
Syros Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (Nasdaq: SYRS), a leader in the development of medicines that control the expression of genes, today announced the grant of restricted stock unit (RSU) awards for an aggregate of 89,400 shares of Syros common stock to three newly hired employees in connection with their commencement of employment with Syros. These RSUs were granted as material inducements to employment in accordance with Nasdaq Listing Rule 5635(c)(4).
By Syros Pharmaceuticals · Via Business Wire · April 1, 2022
Syros Reports Fourth Quarter and Full Year 2021 Financial Results and Highlights Key Accomplishments and Upcoming Milestones
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today reported financial results for the quarter and full-year ended December 31, 2021, and provided an update on recent accomplishments and upcoming events.
By Syros Pharmaceuticals · Via Business Wire · March 15, 2022
Syros to Participate in Upcoming Virtual Investor Conferences in March
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced that its Chief Executive Officer, Nancy Simonian, M.D., will participate in a panel discussion and present a corporate overview at two upcoming virtual investor conferences in March. Management will also be available for one-on-one meetings. Details are as follows:
By Syros Pharmaceuticals · Via Business Wire · February 28, 2022
Syros Receives FDA Orphan Drug Designation for Tamibarotene for the Treatment of MDS
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation (ODD) to tamibarotene for the treatment of myelodysplastic syndrome (MDS). Tamibarotene, an oral first-in-class selective retinoic acid receptor alpha (RARα) agonist, is currently being evaluated in combination with azacitidine in the SELECT-MDS-1 Phase 3 trial for RARA-positive patients with newly diagnosed higher-risk MDS (HR-MDS).
By Syros Pharmaceuticals · Via Business Wire · February 2, 2022
Syros Announces Clinical Updates and 2022 Goals to Support its Advancement to a Fully Integrated Biopharmaceutical Company
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today provided an update on its clinical development programs and outlined its strategic priorities and upcoming expected milestones.
By Syros Pharmaceuticals · Via Business Wire · January 10, 2022
Syros to Participate in Upcoming Investor Conferences
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced that its Chief Executive Officer, Nancy Simonian, M.D., will participate in fireside chats at two upcoming virtual investor conferences. Management will also be available for one-on-one meetings.
By Syros Pharmaceuticals · Via Business Wire · November 16, 2021
Syros Reports Third Quarter 2021 Financial Results and Highlights Key Accomplishments and Upcoming Milestones
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today reported financial results for the quarter ended September 30, 2021, and provided an update on recent accomplishments and upcoming events.
By Syros Pharmaceuticals · Via Business Wire · November 5, 2021
Syros to Report Third Quarter 2021 Financial Results on Friday, November 5, 2021
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced that it will host a live conference call and webcast at 8:30 a.m. ET on Friday, November 5, 2021 to report its third quarter 2021 financial results and provide a corporate update.
By Syros Pharmaceuticals · Via Business Wire · October 29, 2021
Syros Reports Inducement Grant to Chief Financial Officer under Nasdaq Listing Rule 5635(c)(4)
Syros Pharmaceuticals (Nasdaq: SYRS) ("Syros" or the "Company"), a leader in the development of medicines that control the expression of genes, today announced the grant of an inducement stock option award to Jason Haas, the Company’s recently hired Chief Financial Officer, in accordance with Mr. Haas’s employment offer letter. The grant was approved by the Company’s Board of Directors and was made as a material inducement to Mr. Haas’s acceptance of employment with the Company in accordance with Nasdaq Listing Rule 5635(c)(4) as a component of his employment compensation.
By Syros Pharmaceuticals · Via Business Wire · October 13, 2021
Syros Pharmaceuticals Announces Appointment of Jason Haas as Chief Financial Officer
Syros Pharmaceuticals (NASDAQSYRS), a leader in the development of medicines that control the expression of genes, today announced the appointment of Jason Haas as Chief Financial Officer. Mr. Haas brings more than 25 years of healthcare investment banking and corporate finance experience to Syros.
By Syros Pharmaceuticals · Via Business Wire · October 12, 2021